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Custom mRNA Synthesis
At Helix Biotech, we specialize in providing custom mRNA synthesis services designed to meet the specific needs of your research and therapeutic applications. Our expert team employs the latest technology and innovations in IVT (In vitro transcription) mRNA production to ensure that you receive high-quality mRNA that is optimized for expression, stability, and function.
Why Work With Us
Expertise & Experience
Our scientists have years of experience working on different RNA types and therapeutics
Efficient Turnaround
Streamlined processes and innovations to accelerate RNA synthesis and delivery times
High Quality & Purity
Our scientists take measure to reduce dsRNA content and increase RNA purity
How it Works
1. Easily fill out the mRNA Inquiry Form
2. Consultation and Design
3. Rapid Synthesis and Quality Assurance
4. Efficient Delivery to Your Lab
Begin by completing our user-friendly inquiry form, providing essential details about your construct requirements.
Upon receiving your inquiry, our team will promptly review the information and reach out to you within 48 hours with questions or a quote estimate.
Synthesis of your custom mRNA and rigorous quality control measures are implemented to guarantee high purity and functionality of the final product.
Leadtimes as low as 2 weeks
![Abstract Futuristic Background](https://static.wixstatic.com/media/11062b_536bb0dc35e34faaac7844b301768e3a~mv2.jpg/v1/fill/w_471,h_265,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/11062b_536bb0dc35e34faaac7844b301768e3a~mv2.jpg)
Codon Optimization and Sequence Design
We offer codon optimization and sequence design services as part of our custom mRNA synthesis process. Our experts work closely with you to optimize the mRNA sequence for maximal expression and functionality in your specific system.
Streamlined mRNA Production with
Rigorous Quality Control
Our custom mRNA synthesis services are backed by a rigorous quality control process that guarantees the highest levels of purity, potency, and reproducibility.
We utilize a Fragment Bioanalyzer to automate the assessment of mRNA samples, accurately measuring their concentration and ensuring their integrity and purity.
![Water Drops](https://static.wixstatic.com/media/11062b_50d6614af66743168f5e7c6542a0e401~mv2.jpg/v1/fill/w_607,h_444,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/11062b_50d6614af66743168f5e7c6542a0e401~mv2.jpg)
What are the steps involved in Custom mRNA Synthesis?
(1) Codon optimization to enhance transcription efficiency
(2) Gene synthesis and integration into a plasmid DNA (pDNA) vector
(3) Sequence verification to ensure accuracy
(4) pDNA amplification and linearization
(5) in vitro transcription (IVT) mRNA synthesis
(6) mRNA purification and quality control to ensure purity and integrity
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![Abstract DNA Strand](https://static.wixstatic.com/media/11062b_067474dcff474c5ba9434133be95c93c~mv2.jpg/v1/fill/w_637,h_320,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/11062b_067474dcff474c5ba9434133be95c93c~mv2.jpg)