Custom mRNA Synthesis
At Helix Biotech, we specialize in providing custom mRNA synthesis services designed to meet the specific needs of your research and therapeutic applications. Our expert team employs the latest technology and innovations in IVT (In vitro transcription) mRNA production to ensure that you receive high-quality mRNA that is optimized for expression, stability, and function.
What are the steps involved in Custom mRNA Synthesis?
(1) Codon optimization to enhance transcription efficiency
(2) Gene synthesis and integration into a plasmid DNA (pDNA) vector
(3) Sequence verification to ensure accuracy
(4) pDNA amplification and linearization
(5) in vitro transcription (IVT) mRNA synthesis
(6) mRNA purification and quality control to ensure purity and integrity
Turnaround time for custom mRNA synthesis
The turnaround time for custom mRNA synthesis can vary depending on the complexity of the sequence and the required modifications and analytics. Typically, the process takes anywhere from 2-4 weeks. We strive to meet your project timelines and can discuss expedited options if needed.
Leadtimes as low as 2 weeks
Codon Optimization and Sequence Design
We offer codon optimization and sequence design services as part of our custom mRNA synthesis process. Our experts work closely with you to optimize the mRNA sequence for maximal expression and functionality in your specific system.
Streamlined mRNA Production with
Rigorous Quality Control
Our custom mRNA synthesis services are backed by a rigorous quality control process that guarantees the highest levels of purity, potency, and reproducibility.
We utilize a Fragment Bioanalyzer to automate the assessment of mRNA samples, accurately measuring their concentration and ensuring their integrity and purity.
