Ovalbumin (OVA) mRNA (Unmodified) is a synthetic messenger RNA encoding the ovalbumin protein, the predominant glycoprotein found in egg whites. This mRNA is optimized for high expression levels and incorporates N1-methylpseudouridine (Unmodified) modifications to enhance translation efficiency and reduce immunogenicity. It is capped with a Cap-1 structure and includes a poly(A) tail, mimicking fully processed mature mRNA. OVA mRNA (Unmodified) serves as an excellent tool for immunology research, vaccine development, and studies involving antigen presentation and immune responses.
WARNING: This product is not for human or veterinary use.
Available QC Assays
Concentration | Standard, UV-Vis |
A260/280 | Standard, UV-Vis |
Integrity | Standard, Fragment Analysis by Capillary Electrophoresis |
Appearance | Standard |
Endotoxin | Standard, < 10EU/mg |
Purity | IP-RP-HPLC |
RNA Aggregation Assay | SEC-HPLC |
DNA Sequencing | Sanger Sequencing |
dsRNA Content | ELISA |
OVA mRNA (Unmodified)
OVA mRNA (Unmodified) is a synthetic messenger RNA encoding Ovalbumin (OVA), a widely studied model antigen derived from Gallus gallus (chicken egg white). This mRNA is designed for high-efficiency translation in mammalian cells and is widely used in immunology research, antigen presentation studies, vaccine development, and cancer immunotherapy.
Our OVA RNA product is designed to provide researchers with a high-quality and reliable source of this critical tool for their experiments. For research use-only.
Description
Product Name
Ovalbumin (OVA) mRNA Length 1450 nt Modifications N1-methyl-pseudouridine (Unmodified) Appearance Clear, Colorless Solution Buffer 1mM Sodium Citrate, pH 6.4 Purity >90%, Fragment analysis by capillary gel electrophoresis Concentration ~1 mg/mL A260/280 ~2.0 Endotoxin <10 EU/mg Storage ≤ -40°C Shipping Method Dry Ice - Immunotherapy Research: Used as a model antigen for developing mRNA-based cancer vaccines.
- Antigen Presentation Studies: Investigates MHC-I and MHC-II antigen presentation pathways in dendritic cells and T-cell activation.
- In Vivo and In Vitro Studies: Evaluates mRNA delivery, expression kinetics, and immune response in preclinical models.
- Cell Transfection & mRNA-LNP Formulation: Compatible with lipid nanoparticles (LNPs) for efficient delivery in cells and animal models.